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Discovering the
Pathway Between
Chemistry and Biology
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Welcome to the National Institutes of Health (NIH) Chemical Genomics Center (NCGC), a member of the Molecular Libraries Probe Production Center Network. This center has been established by the NIH to create a national resource in chemical probe development. The center uses the latest industrial-scale technologies to collect data that is useful for defining the cross-section between chemical space and biological activity. To learn more about our mission and operations, please spend some time visiting the links above.
>> Recent News

Oct 25, 2009 //
NCGC Scientists Collaborate with Researchers from Trinity College in Dublin, Ireland to Categorize Cytochrome P450 Isozyme Activity. [>> more]

Oct 1, 2009 //
October 9th, 2009 marks the first Frontiers in Science and Medicine Day. This day of activities introduces 7th graders from Shady Grove Middle School to the possibilities of careers in science and medicine. [>> more]

Feb 28, 2009 //
Rare Disease Day 2009. Rare diseases are often chronic, progressive, degenerative, life-threatening and disabling diseases. Many rare disease patients are denied their right to the highest attainable standard of health and continue to advocate their need to overcome common obstacles. [>> more]

Dec 19, 2008 //
International public-private partnership offers new paradigm for medicinal chemistry [>> more]

Nov 25, 2008 //
Chemical Genomics Screen Uncovers Clues to Fat Storage [>> more]

>> Recent Publication

Dec, 2008 //
Beller JA, et al in PLoS Biology. COPI Complex Is a Regulator of Lipid Homeostasis [>> more]

July, 2008 //
Auld DS, et al in ACS Chemical Biology. A Specific Mechanism for Nonspecific Activation in Reporter-Gene Assays [>> more]

April, 2008 //
Readinger JA, et al in PNAS. Selective targeting of ITK blocks multiple steps of HIV replication [>> more]

March, 2008 //
Sayed AA, Simeonov A, et al in Nature Medicine. Identification of oxadiazoles as new drug leads for the control of schistosomiasis [>> more]
>> Assay Guidance Manual

Version 5.0 //
The Latest Version of the Assay Guidance Manual Provides a Wealth of Resources [>> more]